What do systematic reviews say?

Probiotics vs control

Probiotics showed no clear difference in CDAD (baseline risk 3‐5%) compared with control (low certainty).

• Probiotics for the prevention of Clostridium difficile‐associated diarrhea in adults and children 2017 · Cochrane Headline outcomes only
  RR 0.53 [0.16, 1.77]
  3 studies · 373 participants
  Low