Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 2 · 66.7%High 0 · 0%

CDAD (baseline risk >5%) · preventing C. difficile associated diarrhea

Probiotics probably leads to lower CDAD (baseline risk >5%) compared with control (moderate certainty).

1 finding from 1 review

Probiotics for the prevention of Clostridium difficile‐associated diarrhea in adults and children 2017 · Cochrane Headline outcomes only
RR 0.3 [0.21, 0.42]
13 studies · 2454 participants
Moderate

CDAD (baseline risk 0‐2%) · preventing C. difficile associated diarrhea

Probiotics showed no clear difference in CDAD (baseline risk 0‐2%) compared with control (moderate certainty).

1 finding from 1 review

Probiotics for the prevention of Clostridium difficile‐associated diarrhea in adults and children 2017 · Cochrane Headline outcomes only
RR 0.77 [0.45, 1.32]
15 studies · 5845 participants
Moderate

CDAD (baseline risk 3‐5%) · preventing C. difficile associated diarrhea

Probiotics showed no clear difference in CDAD (baseline risk 3‐5%) compared with control (low certainty).

1 finding from 1 review