Phosphodiesterase 4 inhibitors vs placebo
Diarrhoea · patients with stable chronic obstructive pulmonary disease
Phosphodiesterase‐4 inhibitors leads to higher gastrointestinal adverse effects: diarrhoea compared with placebo (high certainty).
1 finding from 1 review
- Phosphodiesterase‐4 inhibitors for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes onlyOR 3.1 [2.74, 3.5]29 studies · 20623 participantsHigh