Findings

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6 questions · 7 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 1 · 14.3%Very low 5 · 71.4%Low 1 · 14.3%Moderate 0 · 0%High 0 · 0%

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Depression: meeting study criteria for depression at end of · people with depression after stroke

Pharmacological intervention and non‐invasive brain stimulation… may leads to lower depression: meeting the criteria for depression at end of treatment… compared with a pharmacological intervention and sham stimulation or usual care… (low certainty).

2 findings from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
RR 0.77 [0.64, 0.91]
3 studies · 392 participants
Low
Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Depression: < 50% reduction in scale scores at end of treatment (primary outcome) · people with depression after stroke

It is very uncertain whether pharmacological intervention and non‐invasive brain stimulation… changes depression: < 50% reduction in scale scores at end of treatment… compared with a pharmacological intervention and sham stimulation or usual care… (very low certainty).

1 finding from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
RR 0.95 [0.69, 1.3]
3 studies · 392 participants
Very low

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Depression: mean scores at end of treatment (secondary outcome) · people with depression after stroke

1 finding from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 1055 participants
Very low

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Adverse events: death ‐ at end of treatment (secondary outcome) · people with depression after stroke

It is very uncertain whether pharmacological intervention and non‐invasive brain stimulation… changes adverse events: death (secondary outcome) compared with a pharmacological intervention and sham stimulation or usual care… (very low certainty).

1 finding from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
RR 1.06 [0.27, 4.16]
5 studies · 487 participants
Very low

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Adverse events: all ‐ central nervous system events (e.g. headache, seizures) (secondary outcome) · people with depression after stroke

It is very uncertain whether pharmacological intervention and non‐invasive brain stimulation… changes adverse events: all ‐ central nervous system events (e.g. headache,… compared with a pharmacological intervention and sham stimulation or usual care… (very low certainty).

1 finding from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
RR 0.5 [0.05, 5.28]
3 studies · 342 participants
Very low

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Adverse events: all ‐ other events ‐ not listed above (e.g. dysuria, neck pain, eye discomfort) (secondary outcome) · people with depression after stroke

It is very uncertain whether pharmacological intervention and non‐invasive brain stimulation… changes adverse events: all ‐ other events ‐ not listed above (e.g.… compared with a pharmacological intervention and sham stimulation or usual care… (very low certainty).

1 finding from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
RR 7 [0.38, 129.93]
2 studies · 120 participants
Very low