Findings

What do systematic reviews say?

8 questions · 11 findings · 1 reviews

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No studies found 2 · 18.2%GRADE not reported 0 · 0%Very low 9 · 81.8%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Phamacotherapies that specifically target ammonia vs placebo or non‐absorbable disaccharides

All‐cause mortality · adults with cirrhosis and hepatic encephalopathy

1 finding from 1 review

Pharmacotherapies that specifically target ammonia for the prevention and treatment of hepatic encephalopathy in… 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low

Phamacotherapies that specifically target ammonia vs placebo or non‐absorbable disaccharides

Blood ammonia concentrations (units unspecified) · adults with cirrhosis and hepatic encephalopathy

3 findings from 1 review

Pharmacotherapies that specifically target ammonia for the prevention and treatment of hepatic encephalopathy in… 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 35 participants
Very low
Pharmacotherapies that specifically target ammonia for the prevention and treatment of hepatic encephalopathy in… 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low
Pharmacotherapies that specifically target ammonia for the prevention and treatment of hepatic encephalopathy in… 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 231 participants
Very low

Phamacotherapies that specifically target ammonia vs placebo or non‐absorbable disaccharides

Blood ammonia concentrations (µmol/L*week) · adults with cirrhosis and hepatic encephalopathy

2 findings from 1 review

Pharmacotherapies that specifically target ammonia for the prevention and treatment of hepatic encephalopathy in… 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 90 participants
Very low
Pharmacotherapies that specifically target ammonia for the prevention and treatment of hepatic encephalopathy in… 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 178 participants
Very low

Phamacotherapies that specifically target ammonia vs placebo or non‐absorbable disaccharides

Hepatic encephalopathy · adults with cirrhosis and hepatic encephalopathy

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacotherapies that specifically target ammonia for the prevention and treatment of hepatic encephalopathy in… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Phamacotherapies that specifically target ammonia vs placebo or non‐absorbable disaccharides

Serious adverse events · adults with cirrhosis and hepatic encephalopathy

1 finding from 1 review

Pharmacotherapies that specifically target ammonia for the prevention and treatment of hepatic encephalopathy in… 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low

Phamacotherapies that specifically target ammonia vs placebo or non‐absorbable disaccharides

Non‐serious adverse events · adults with cirrhosis and hepatic encephalopathy

1 finding from 1 review

Pharmacotherapies that specifically target ammonia for the prevention and treatment of hepatic encephalopathy in… 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low

Phamacotherapies that specifically target ammonia vs placebo or non‐absorbable disaccharides

Health‐related quality of life · adults with cirrhosis and hepatic encephalopathy

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacotherapies that specifically target ammonia for the prevention and treatment of hepatic encephalopathy in… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Phamacotherapies that specifically target ammonia vs placebo or non‐absorbable disaccharides

Plasma ammonia concentration (µmol/L) · adults with cirrhosis and hepatic encephalopathy

1 finding from 1 review

Pharmacotherapies that specifically target ammonia for the prevention and treatment of hepatic encephalopathy in… 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 85 participants
Very low