Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

7 questions · 12 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 12 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Laser fluorescence (DIAGNOdent 2190/pen) vs Reference standard (histology, excavation, or enhanced visual examination)

Diagnostic accuracy (pooled sensitivity, specificity, diagnostic odds ratio, summary-ROC AUC) · Permanent teeth, occlusal surfaces, with suspected caries lesions

Pen-type laser fluorescence on occlusal surfaces of permanent teeth (more advanced-lesion threshold): pooled DOR for LFpen lower than for LF and FC; heterogeneity I2=73%. Diagnostic accuracy was not formally graded (GRADE not used).

2 findings from 1 review

Laser fluorescence (DIAGNOdent 2190/pen) vs Reference standard (histology, excavation, or enhanced visual examination)

Relative DOR by reference standard (LFpen, initial, occlusal permanent) · Permanent teeth, occlusal surfaces, with suspected caries lesions

No significant reference-standard difference for LFpen at the initial threshold (RDOR 4.41, 0.19 to 103.92).

1 finding from 1 review

Laser fluorescence (DIAGNOdent 2190/pen) vs Reference standard (histology, excavation, or enhanced visual examination)

Diagnostic accuracy (pooled sensitivity, specificity, diagnostic odds ratio, summary-ROC AUC) · Primary teeth, occlusal surfaces, with suspected caries lesions

Pen-type laser fluorescence on occlusal surfaces of primary teeth (more advanced-lesion threshold): pooled DOR intermediate for LFpen among the three methods; heterogeneity I2=31%. Diagnostic accuracy was not formally graded (GRADE not used).

2 findings from 1 review

Laser fluorescence (DIAGNOdent 2190/pen) vs Reference standard (histology, excavation, or enhanced visual examination)

Diagnostic accuracy (pooled sensitivity, specificity, diagnostic odds ratio, summary-ROC AUC) · Permanent teeth, approximal surfaces, with suspected caries lesions

Pen-type laser fluorescence on approximal surfaces of permanent teeth (more advanced-lesion threshold): LFpen showed similar values at both thresholds; heterogeneity I2=84%. Diagnostic accuracy was not formally graded (GRADE not used).

2 findings from 1 review

Laser fluorescence (DIAGNOdent 2190/pen) vs Reference standard (histology, excavation, or enhanced visual examination)

Relative DOR by setting (LFpen, advanced, occlusal permanent) · Permanent teeth, occlusal surfaces, with suspected caries lesions

No significant setting difference for LFpen (RDOR 0.35, 0.04 to 2.99).

2 findings from 1 review

Laser fluorescence (DIAGNOdent 2190/pen) vs Reference standard (histology, excavation, or enhanced visual examination)

Diagnostic accuracy (pooled sensitivity, specificity, diagnostic odds ratio, summary-ROC AUC) · Primary teeth, approximal surfaces, with suspected caries lesions

Pen-type laser fluorescence on approximal surfaces of primary teeth (initial-lesion threshold): only LFpen had sufficient studies to pool; heterogeneity I2=84%. Diagnostic accuracy was not formally graded (GRADE not used).

2 findings from 1 review

Laser fluorescence (DIAGNOdent 2190/pen) vs Reference standard (histology, excavation, or enhanced visual examination)

Relative DOR by reference standard (LFpen, advanced, occlusal permanent) · Permanent teeth, occlusal surfaces, with suspected caries lesions

No significant reference-standard difference for LFpen at the advanced threshold (RDOR 0.96, 0.12 to 7.77).

1 finding from 1 review