Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 7 · 100%High 0 · 0%

Failure to respond at endpoint (6‐12 weeks) · patients with depression

Paroxetine showed no clear difference in failure to respond at endpoint (6‐12 weeks) compared with mirtazapine (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 1.2 [0.9, 1.61]
4 studies · 766 participants
Moderate

Failure to respond at 1‐4 weeks · patients with depression

Paroxetine probably leads to higher failure to respond at 1‐4 weeks compared with mirtazapine (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 2.39 [1.42, 4.02]
3 studies · 726 participants
Moderate

Failure to respond at 16‐24 weeks · patients with depression

Paroxetine showed no clear difference in failure to respond at 16‐24 weeks compared with mirtazapine (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 1.41 [0.81, 2.48]
3 studies · 726 participants
Moderate

Failure to remit at endpoint · patients with depression

Paroxetine probably leads to higher failure to remit at endpoint compared with mirtazapine (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 1.52 [1.13, 2.06]
4 studies · 766 participants
Moderate

SMD at endpoint · patients with depression

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 246 participants
Moderate

Failure to complete ‐ any cause ‐ · patients with depression

Paroxetine showed no clear difference in failure to complete ‐ any cause ‐ compared with mirtazapine (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 1.26 [0.91, 1.74]
3 studies · 726 participants
Moderate

Participants with at least some Side Effects · patients with depression

Paroxetine showed no clear difference in participants with at least some Side Effects compared with mirtazapine (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 1.07 [0.76, 1.5]
3 studies · 726 participants
Moderate