Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Pregnancy and Childbirth

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 14.3%Low 3 · 42.9%Moderate 3 · 42.9%High 0 · 0%

Manual removal of the placenta · management of retained placenta

Oxytocin solution may leads to lower manual removal of the placenta compared with saline solution (low certainty).

1 finding from 1 review

Umbilical vein injection for management of retained placenta 2021 · Cochrane Headline outcomes only
RR 0.82 [0.69, 0.97]
14 studies · 1370 participants
Low

Maternal death · management of retained placenta

Oxytocin solution showed no clear difference in maternal mortality compared with saline solution (low certainty).

1 finding from 1 review

Umbilical vein injection for management of retained placenta 2021 · Cochrane Headline outcomes only
RR 2.93 [0.12, 71.59]
5 studies · 782 participants
Low

Severe PPH (≥ 1000 mL) · management of retained placenta

Oxytocin solution showed no clear difference in severe PPH (≥ 1000 mL) compared with saline solution (moderate certainty).

1 finding from 1 review

Umbilical vein injection for management of retained placenta 2021 · Cochrane Headline outcomes only
RR 1.08 [0.7, 1.68]
4 studies · 766 participants
Moderate

Blood transfusion · management of retained placenta

Oxytocin solution showed no clear difference in blood transfusion compared with saline solution (moderate certainty).

1 finding from 1 review

Umbilical vein injection for management of retained placenta 2021 · Cochrane Headline outcomes only
RR 1.08 [0.78, 1.49]
7 studies · 974 participants
Moderate

Addition of therapeutic uterotonics · management of retained placenta

Oxytocin solution showed no clear difference in addition of therapeutic uterotonics compared with saline solution (low certainty).

1 finding from 1 review

Umbilical vein injection for management of retained placenta 2021 · Cochrane Headline outcomes only
RR 0.85 [0.59, 1.23]
4 studies · 678 participants
Low

Need for antibiotics · management of retained placenta

Oxytocin solution showed no clear difference in need for treatment with antibiotics (infection) compared with saline solution (moderate certainty).

1 finding from 1 review

Umbilical vein injection for management of retained placenta 2021 · Cochrane Headline outcomes only
RR 1.26 [0.81, 1.96]
2 studies · 635 participants
Moderate

Maternal postpartum anaemia (haemoglobin 24–48 hours postpartum) · management of retained placenta

1 finding from 1 review

Umbilical vein injection for management of retained placenta 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 167 participants
Very low