Findings

What do systematic reviews say?

22 questions · 22 findings · 3 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 13.6%Low 5 · 22.7%Moderate 13 · 59.1%High 1 · 4.5%

Oxcarbazepine vs phenytoin

Time to first seizure (post‐randomisation) Subgroup: generalised onset seizures Range of · people with newly diagnosed epilepsy

Summary of findings: oxcarbazepine showed no clear difference in time to first seizure (post‐randomisation) Subgroup: generalised… compared with phenytoin (secondary outcomes) (low certainty).

1 finding from 1 review

Oxcarbazepine versus phenytoin monotherapy for epilepsy: an individual participant data review 2018 · Cochrane Headline outcomes only
HR 1.11 [0.66, 1.86]
2 studies · 142 participants
Low

Oxcarbazepine vs phenytoin

Remission · people with newly diagnosed epilepsy

Summary of findings: oxcarbazepine showed no clear difference in time to achieve 12‐month remission (seizure‐free period) All… compared with phenytoin (secondary outcomes) (moderate certainty).

1 finding from 1 review

Oxcarbazepine versus phenytoin monotherapy for epilepsy: an individual participant data review 2018 · Cochrane Headline outcomes only
HR 1.04 [0.77, 1.41]
2 studies · 468 participants
Moderate