Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 3 · 100%High 0 · 0%

Oral 5‐aminosalicylic acid vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)

Exclusion/withdrawal after entry · Patients with quiescent ulcerative colitis

Oral 5‐aminosalicylic acid showed no clear difference in exclusion/withdrawal after entry compared with comparator 5‐aminosalicylic acid formulation (moderate certainty).

1 finding from 1 review

Oral 5‐aminosalicylic acid for maintenance of remission in ulcerative colitis 2020 · Cochrane Headline outcomes only
RR 1.23 [0.9, 1.7]
5 studies · 457 participants
Moderate

Oral 5‐aminosalicylic acid vs sulfasalazine

Exclusion/withdrawal after entry · Patients with quiescent ulcerative colitis

Oral 5‐aminosalicylic acid probably leads to higher exclusion/withdrawal after entry compared with sulfasalazine (moderate certainty).

1 finding from 1 review

Oral 5‐aminosalicylic acid for maintenance of remission in ulcerative colitis 2020 · Cochrane Headline outcomes only
RR 1.3 [1.04, 1.63]
9 studies · 1497 participants
Moderate

Oral 5‐aminosalicylic acid vs placebo

Exclusion/withdrawal after entry · Patients with quiescent ulcerative colitis

Oral 5‐aminosalicylic acid showed no clear difference in exclusion/withdrawal after entry compared with placebo (moderate certainty).

1 finding from 1 review

Oral 5‐aminosalicylic acid for maintenance of remission in ulcerative colitis 2020 · Cochrane Headline outcomes only
RR 1.13 [0.88, 1.44]
5 studies · 1074 participants
Moderate