Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 66.7%High 1 · 33.3%

Failure to induce global or clinical remission · Patients with active mild to moderate ulcerative colitis

Oral 5‐ASA showed no clear difference in failure to induce global or clinical remission compared with comparator 5‐ASA (moderate certainty).

1 finding from 1 review

Oral 5‐aminosalicylic acid for induction of remission in ulcerative colitis 2020 · Cochrane Headline outcomes only
RR 0.94 [0.86, 1.02]
11 studies · 1968 participants
Moderate

Failure to induce global or clinical remission · Patients with active mild to moderate ulcerative colitis

Oral 5‐ASA showed no clear difference in failure to induce global or clinical remission compared with SASP (moderate certainty).

1 finding from 1 review

Oral 5‐aminosalicylic acid for induction of remission in ulcerative colitis 2020 · Cochrane Headline outcomes only
RR 0.9 [0.77, 1.04]
8 studies · 526 participants
Moderate

Failure to induce global or clinical remission · Patients with active mild to moderate ulcerative colitis

Oral 5‐ASA leads to lower failure to induce complete global or clinical remission compared with placebo (high certainty).

1 finding from 1 review

Oral 5‐aminosalicylic acid for induction of remission in ulcerative colitis 2020 · Cochrane Headline outcomes only
RR 0.86 [0.82, 0.89]
11 studies · 2387 participants
High