Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 66.7%High 1 · 33.3%

Failure to induce global or clinical improvement · Patients with active mild to moderate ulcerative colitis

Oral 5‐ASA probably leads to lower failure to induce global or clinical improvement compared with placebo (moderate certainty).

1 finding from 1 review

Oral 5‐aminosalicylic acid for induction of remission in ulcerative colitis 2020 · Cochrane Headline outcomes only
RR 0.68 [0.61, 0.75]
14 studies · 2256 participants
Moderate

Failure to induce global or clinical improvement · Patients with active mild to moderate ulcerative colitis

Oral 5‐ASA showed no clear difference in failure to induce global or clinical improvement compared with comparator 5‐ASA (moderate certainty).

1 finding from 1 review

Oral 5‐aminosalicylic acid for induction of remission in ulcerative colitis 2020 · Cochrane Headline outcomes only
RR 0.89 [0.77, 1.01]
8 studies · 1647 participants
Moderate

Failure to induce global or clinical improvement · Patients with active mild to moderate ulcerative colitis

Oral 5‐ASA showed no clear difference in failure to induce global or clinical improvement compared with SASP (high certainty).

1 finding from 1 review

Oral 5‐aminosalicylic acid for induction of remission in ulcerative colitis 2020 · Cochrane Headline outcomes only
RR 0.88 [0.76, 1.01]
14 studies · 1053 participants
High