Hand‐foot syndrome (grade ≥ 3) · Patients treated with palliative intent for inoperable advanced or metastatic colorectal cancer with chemotherapy
Oral probably leads to higher grade ≥ 3 hand foot syndrome compared with intravenous fluoropyrimidines (moderate certainty).
1 finding from 1 review
All‐cause mortality · people with cancer who have febrile neutropenia
Oral showed no clear difference in mortality compared with intravenous antibiotic therapy (moderate certainty).
1 finding from 1 review
Treatment failure · people with cancer who have febrile neutropenia
Oral showed no clear difference in treatment failure compared with intravenous antibiotic therapy (moderate certainty).
1 finding from 1 review
Treatment failure ‐ per protocol analysis · people with cancer who have febrile neutropenia
Oral showed no clear difference in treatment failure ‐ per protocol analysis compared with intravenous antibiotic therapy (moderate certainty).
1 finding from 1 review
Adverse events requiring discontinuation of antibiotics · people with cancer who have febrile neutropenia
Oral showed no clear difference in adverse events requiring discontinuation of antibiotics compared with intravenous antibiotic therapy (low certainty).
1 finding from 1 review
Treatment failure not dt modification in update · people with cancer who have febrile neutropenia
Oral showed no clear difference in treatment failure not dt modification in update compared with intravenous antibiotic therapy (moderate certainty).
1 finding from 1 review
All‐cause mortality · people with paracetamol (acetaminophen) overdose
1 finding from 1 review
Hepatotoxicity · people with paracetamol (acetaminophen) overdose
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Nausea · people with paracetamol (acetaminophen) overdose
It is very uncertain whether oral changes nausea compared with intravenous acetylcysteine (very low certainty).
1 finding from 1 review
Vomiting · people with paracetamol (acetaminophen) overdose
It is very uncertain whether oral changes vomiting compared with intravenous acetylcysteine (very low certainty).
1 finding from 1 review
Vaginal birth within 24 hours · women in the third trimester for induction of labour.
Oral misoprostol showed no clear difference in vaginal birth within 24 hours compared with intravenous oxytocin (low certainty).
1 finding from 1 review
Caesarean section · women in the third trimester for induction of labour.
Oral misoprostol probably leads to lower caesarean section compared with intravenous oxytocin (moderate certainty).
1 finding from 1 review
Uterine hyperstimulation with fetal heart rate changes · women in the third trimester for induction of labour.
It is very uncertain whether oral misoprostol changes uterine hyperstimulation with fetal heart rate changes compared with intravenous oxytocin (very low certainty).
1 finding from 1 review
Oxytocin augmentation · women in the third trimester for induction of labour.
Oral misoprostol may leads to lower oxytocin augmentation compared with intravenous oxytocin (low certainty).
1 finding from 1 review
Uterine hyperstimulation without fetal heart rate changes · women in the third trimester for induction of labour.
It is very uncertain whether oral misoprostol changes uterine hyperstimulation without fetal heart rate changes compared with intravenous oxytocin (very low certainty).
1 finding from 1 review
Apgar score less than 7 at 5 minutes · women in the third trimester for induction of labour.
It is very uncertain whether oral misoprostol changes apgar score less than 7 at 5 minutes compared with intravenous oxytocin (very low certainty).
1 finding from 1 review
Admission to neonatal intensive care unit · women in the third trimester for induction of labour.
It is very uncertain whether oral misoprostol changes admission to neonatal intensive care unit compared with intravenous oxytocin (very low certainty).
1 finding from 1 review
All‐cause mortality during hospital stay and all‐cause mortality at 1 year · people with endocarditis on the left side of the heart (on native or prosthetic valves) with bacteraemia for Streptococcus, Enterococcus…
It is very uncertain whether partial oral treatment changes all‐cause mortality during hospital stay and all‐cause mortality at… compared with conventional intravenous treatment of endocarditis on the left side… (very low certainty).
1 finding from 1 review
Cure · people with endocarditis on the left side of the heart (on native or prosthetic valves) with bacteraemia for Streptococcus, Enterococcus…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · people with endocarditis on the left side of the heart (on native or prosthetic valves) with bacteraemia for Streptococcus, Enterococcus…
Partial oral treatment showed no clear difference in adverse events compared with conventional intravenous treatment of endocarditis on the left side… (low certainty).
1 finding from 1 review