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Evidence found and GRADE certainty

1,809 questions · 1,956 findings · 194 reviews

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No studies found 422 · 21.6%GRADE not reported 427 · 21.8%Very low 353 · 18%Low 397 · 20.3%Moderate 293 · 15%High 64 · 3.3%

Oral factor Xa inhibitors vs conventional anticoagulation

Non‐fatal PE (3 to 12 months) · participants with diagnosed DVT

Oral factor Xa inhibitors showed no clear difference in non‐fatal PE (3 to 12 months) compared with conventional anticoagulation (moderate certainty).

1 finding from 1 review

Oral factor Xa inhibitors vs conventional anticoagulation

All‐cause mortality (3 to 6 months) · participants with diagnosed DVT

Oral factor Xa inhibitors showed no clear difference in all‐cause mortality (3 to 6 months) compared with conventional anticoagulation (moderate certainty).

1 finding from 1 review

Oral factor Xa inhibitors vs conventional anticoagulation

Recurrent DVT (3 to 12 months) · participants with diagnosed DVT

Oral factor Xa inhibitors showed no clear difference in recurrent DVT (3 to 12 months) compared with conventional anticoagulation (moderate certainty).

1 finding from 1 review

Oral factor Xa inhibitors vs conventional anticoagulation

Fatal PE (3 to 12 months) · participants with diagnosed DVT

Oral factor Xa inhibitors showed no clear difference in fatal PE (3 to 12 months) compared with conventional anticoagulation (moderate certainty).

1 finding from 1 review

Oral factor Xa inhibitors vs conventional anticoagulation

All‐cause mortality · patients with a pulmonary embolism, confirmed by standard imaging techniques

Oral factor Xa inhibitors showed no clear difference in all‐cause mortality compared with conventional anticoagulation (moderate certainty).

1 finding from 1 review

Oral factor Xa inhibitors vs conventional anticoagulation

Major bleedinge · patients with a pulmonary embolism, confirmed by standard imaging techniques

Oral factor Xa inhibitors showed no clear difference in major bleedinge compared with conventional anticoagulation (low certainty).

1 finding from 1 review

Oral factor Xa inhibitors vs conventional anticoagulation

Recurrent PE · patients with a pulmonary embolism, confirmed by standard imaging techniques

Oral factor Xa inhibitors showed no clear difference in recurrent PEa compared with conventional anticoagulation (moderate certainty).

1 finding from 1 review

Oral factor Xa inhibitors vs conventional anticoagulation

Recurrent VTEc · patients with a pulmonary embolism, confirmed by standard imaging techniques

Oral factor Xa inhibitors showed no clear difference in recurrent VTEc compared with conventional anticoagulation (moderate certainty).

1 finding from 1 review

Oral factor Xa inhibitors vs conventional anticoagulation

DVTd · patients with a pulmonary embolism, confirmed by standard imaging techniques

Oral factor Xa inhibitors showed no clear difference in DVTd compared with conventional anticoagulation (moderate certainty).

1 finding from 1 review

Transbuccal miniplate combined with intraoral approach vs Intraoral approach alone

Requirement for additional (surgical) interventions (plate removal within 90 days) · Adults with fractures of the mandibular angle

Transbuccal miniplate combined with intraoral approach led to lower requirement for additional (surgical) interventions (plate removal… compared with intraoral approach alone; GRADE not reported.

1 finding from 1 review

Transbuccal miniplate combined with intraoral approach vs Intraoral approach alone

Restoration of function (malocclusion; interincisor mouth opening) · Adults with fractures of the mandibular angle
1 finding from 1 review
  • Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes
    3 months · Angle of mandible only
    Persistent malocclusion was minimal, reported in one participant in each group at the 3-month follow-up. Mean interincisor mouth opening at 3 months 37.68 mm (range 17 to 50) combined approach vs 38.19 mm (range 22 to…
    1 study
    GRADE not reported

Transbuccal miniplate combined with intraoral approach vs Intraoral approach alone

Post-operative infection (persistent) · Adults with fractures of the mandibular angle

Transbuccal miniplate combined with intraoral approach showed no clear difference in post-operative infection (persistent) compared with intraoral approach alone; GRADE not reported.

1 finding from 1 review