Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Pregnancy and Childbirth

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No studies found 2 · 28.6%GRADE not reported 0 · 0%Very low 0 · 0%Low 5 · 71.4%Moderate 0 · 0%High 0 · 0%

Ondansetron vs control

Maternal hypotension requiring intervention · women having spinal anaesthesia for caesarean section

Ondansetron may leads to lower maternal hypotension requiring intervention compared with control (low certainty).

1 finding from 1 review

Techniques for preventing hypotension during spinal anaesthesia for caesarean section 2020 · Cochrane Headline outcomes only
RR 0.67 [0.54, 0.83]
8 studies · 740 participants
Low

Ondansetron vs control

Maternal hypertension requiring intervention · women having spinal anaesthesia for caesarean section

The review found no eligible studies for this question.

1 finding from 1 review

Techniques for preventing hypotension during spinal anaesthesia for caesarean section 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Ondansetron vs control

Maternal bradycardia requiring intervention · women having spinal anaesthesia for caesarean section

Ondansetron may leads to lower maternal bradycardia requiring intervention compared with control (low certainty).

1 finding from 1 review

Techniques for preventing hypotension during spinal anaesthesia for caesarean section 2020 · Cochrane Headline outcomes only
RR 0.49 [0.28, 0.87]
8 studies · 740 participants
Low

Ondansetron vs control

Maternal nausea and/or vomiting · women having spinal anaesthesia for caesarean section

Ondansetron may leads to lower maternal nausea and/or vomiting compared with control (low certainty).

1 finding from 1 review

Techniques for preventing hypotension during spinal anaesthesia for caesarean section 2020 · Cochrane Headline outcomes only
RR 0.35 [0.24, 0.51]
7 studies · 653 participants
Low

Ondansetron vs control

Neonatal Apgar score < 8 at 5 minutes · women having spinal anaesthesia for caesarean section

1 finding from 1 review

Techniques for preventing hypotension during spinal anaesthesia for caesarean section 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 284 participants
Low

Ondansetron vs control

Neonatal acidosis as defined by cord or neonatal blood with a pH < 7.2 · women having spinal anaesthesia for caesarean section

Ondansetron showed no clear difference in neonatal acidosis as defined by cord or neonatal blood with a pH < 7.2 compared with control (low certainty).

1 finding from 1 review

Techniques for preventing hypotension during spinal anaesthesia for caesarean section 2020 · Cochrane Headline outcomes only
RR 0.48 [0.05, 5.09]
2 studies · 134 participants
Low

Ondansetron vs control

Neonatal unit admission · women having spinal anaesthesia for caesarean section

The review found no eligible studies for this question.

1 finding from 1 review

Techniques for preventing hypotension during spinal anaesthesia for caesarean section 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found