Findings

What do systematic reviews say?

8 questions · 8 findings · 1 reviews

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No studies found 5 · 62.5%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 37.5%Moderate 0 · 0%High 0 · 0%

Non‐steroidal mineralocorticoid receptor antagonist vs selective aldosterone antagonist

Kidney failure · proteinuric chronic kidney disease

The review found no eligible studies for this question.

1 finding from 1 review

Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Non‐steroidal mineralocorticoid receptor antagonist vs selective aldosterone antagonist

Hyperkalaemia · proteinuric chronic kidney disease

Non‐steroidal mineralocorticoid receptor antagonist showed no clear difference in hyperkalaemia compared with selective aldosterone antagonist (low certainty).

1 finding from 1 review

Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
RR 0.89 [0.45, 1.77]
1 study · 1023 participants
Low

Non‐steroidal mineralocorticoid receptor antagonist vs selective aldosterone antagonist

Death · proteinuric chronic kidney disease

Non‐steroidal mineralocorticoid receptor antagonist showed no clear difference in death compared with selective aldosterone antagonist (low certainty).

1 finding from 1 review

Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
RR 0.7 [0.31, 1.55]
1 study · 1055 participants
Low

Non‐steroidal mineralocorticoid receptor antagonist vs selective aldosterone antagonist

Cardiovascular events · proteinuric chronic kidney disease

The review found no eligible studies for this question.

1 finding from 1 review

Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Non‐steroidal mineralocorticoid receptor antagonist vs selective aldosterone antagonist

Doubling serum creatinine · proteinuric chronic kidney disease

Non‐steroidal mineralocorticoid receptor antagonist showed no clear difference in doubling serum creatinine compared with selective aldosterone antagonist (low certainty).

1 finding from 1 review

Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
RR 0.8 [0.03, 19.51]
1 study · 1055 participants
Low

Non‐steroidal mineralocorticoid receptor antagonist vs selective aldosterone antagonist

AKI · proteinuric chronic kidney disease

The review found no eligible studies for this question.

1 finding from 1 review

Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Non‐steroidal mineralocorticoid receptor antagonist vs selective aldosterone antagonist

Proteinuria · proteinuric chronic kidney disease

The review found no eligible studies for this question.

1 finding from 1 review

Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Non‐steroidal mineralocorticoid receptor antagonist vs selective aldosterone antagonist

eGFR · proteinuric chronic kidney disease

The review found no eligible studies for this question.

1 finding from 1 review

Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found