Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 2 · 66.7%High 0 · 0%

Non‐invasive ventilation vs usual care

All‐cause mortality · Patients admitted to hospital with acute hypercapnic respiratory failure due to an exacerbation of chronic obstructive pulmonary disease…

Non‐invasive ventilation probably leads to lower mortality compared with usual medical care (moderate certainty).

1 finding from 1 review

Non‐invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of chronic… 2017 · Cochrane Headline outcomes only
RR 0.54 [0.38, 0.76]
12 studies · 854 participants
Moderate

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs standard treatment following a severe exacerbation

All‐cause mortality · post‐exacerbation COPD

Summary of Findings Table ‐ Chronic non‐invasive ventilation showed no clear difference in all‐cause mortality compared with standard treatment following a severe exacerbation (low certainty).

1 finding from 1 review

Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
HR 0.97 [0.74, 1.28]
2 studies · 318 participants
Low

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs usual care

All‐cause mortality · stable COPD

Summary of Findings Table ‐ Chronic non‐invasive ventilation probably leads to lower all‐cause mortality compared with standard treatment (moderate certainty).

1 finding from 1 review

Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
HR 0.75 [0.58, 0.97]
3 studies · 405 participants
Moderate