Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Oral and maxillofacial surgery

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No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Naproxen vs placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…

Oral naproxen (NSAID) led to lower pain intensity (VAS) compared with placebo; GRADE not reported.

1 finding from 1 review

Pharmacological interventions for pain in patients with temporomandibular disorders 2010 · Cochrane All outcomes
6 weeks
MD -1.70 [-2.14, -1.25]
1 study · 68 participants
GRADE not reported

Naproxen vs placebo

Adverse events (reported; mild, no withdrawals) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…

1 finding from 1 review

Pharmacological interventions for pain in patients with temporomandibular disorders 2010 · Cochrane All outcomes
6 weeks
Ta and Dionne 2004 (naproxen) reported adverse effects. Per the review: 'All but one study (Lobo et al 2004) reported adverse effects. Most of the reported adverse effects were mild and similar to the adverse effects…
1 study · 68 participants
GRADE not reported