Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 100%High 0 · 0%

Total mortality · Men and non‐pregnant women ≥ 18 years old with essential hypertension

Naltrexone/bupropion showed no clear difference in total mortality compared with placebo (moderate certainty).

1 finding from 1 review

Long‐term effects of weight‐reducing drugs in people with hypertension 2021 · Cochrane Headline outcomes only
RR 0.99 [0.7, 1.4]
1 study · 8283 participants
Moderate