Findings

What do systematic reviews say?

23 questions · 24 findings · 1 reviews

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No studies found 3 · 12.5%GRADE not reported 0 · 0%Very low 9 · 37.5%Low 7 · 29.2%Moderate 3 · 12.5%High 2 · 8.3%

NSAIDs vs paracetamol

Neurological adverse effects · people with acute soft tissue injury, such as ankle sprain

NSAID showed no clear difference in neurological adverse events compared with paracetamol (low certainty).

1 finding from 1 review

Oral non‐steroidal anti‐inflammatory drugs versus other oral analgesic agents for acute soft tissue injury 2020 · Cochrane Headline outcomes only
RR 0.85 [0.62, 1.17]
9 studies · 1679 participants
Low

NSAIDs vs paracetamol

Early re‐injury (with 3 months) · people with acute soft tissue injury, such as ankle sprain

The review found no eligible studies for this question.

1 finding from 1 review

Oral non‐steroidal anti‐inflammatory drugs versus other oral analgesic agents for acute soft tissue injury 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

NSAIDs vs opioid

Reduction in pain intensity · acute soft tissue injury

1 finding from 1 review

Oral non‐steroidal anti‐inflammatory drugs versus other oral analgesic agents for acute soft tissue injury 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1058 participants
Moderate