Findings

What do systematic reviews say?

4 questions · 7 findings · 1 reviews · Periodontology

No studies found 0 · 0%GRADE not reported 7 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Adverse events · Adults with chronic periodontitis

Moxifloxacin + SRP showed no clear difference in adverse events compared with SRP; GRADE not reported.

1 finding from 1 review

Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
The included trial (Ardila 2015) had no adverse events amongst the participants.
1 study · 40 participants
GRADE not reported

Probing pocket depth · Adults with chronic periodontitis

Moxifloxacin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.

2 findings from 1 review

Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Intermediate-term (> 3 months to < 1 year)
MD -0.42 [-0.74, -0.10]
1 study · 40 participants
GRADE not reported
Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Short-term (≤ 3 months)
MD -0.55 [-0.87, -0.23]
1 study · 40 participants
GRADE not reported

Clinical attachment level (CAL) · Adults with chronic periodontitis

Moxifloxacin + SRP led to lower clinical attachment level (CAL) compared with SRP; GRADE not reported.

2 findings from 1 review

Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Short-term (≤ 3 months)
MD -0.67 [-1.01, -0.33]
1 study · 40 participants
GRADE not reported
Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Intermediate-term (> 3 months to < 1 year)
MD -0.63 [-0.95, -0.31]
1 study · 40 participants
GRADE not reported

Percentage of bleeding on probing (BOP) · Adults with chronic periodontitis

Moxifloxacin + SRP led to lower percentage of bleeding on probing (BOP) compared with SRP; GRADE not reported.

2 findings from 1 review

Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Short-term (≤ 3 months)
MD -3.40 [-3.72, -3.08]
1 study · 40 participants
GRADE not reported
Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Intermediate-term (> 3 months to < 1 year)
MD -0.80 [-1.12, -0.48]
1 study · 40 participants
GRADE not reported