Findings

What do systematic reviews say?

22 questions · 22 findings · 4 reviews

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No studies found 2 · 9.1%GRADE not reported 0 · 0%Very low 7 · 31.8%Low 7 · 31.8%Moderate 1 · 4.5%High 5 · 22.7%

Augmentation of current antidepressant (SSRI/SNRI) with mirtazapine (30 mg/d) vs augmentation of current antidepressant (various) with placebo

Remission · treatment‐resistant depression in adults

Augmentation of current antidepressant (SSRI/SNRI) with mirtazapine… showed no clear difference in remission (BDI‐II total score ≤ 9) compared with augmentation of current antidepressant (SSRI/SNRI) therapy with… (high certainty).

1 finding from 1 review

Pharmacological interventions for treatment‐resistant depression in adults 2019 · Cochrane Headline outcomes only
RR 1.21 [0.88, 1.65]
1 study · 431 participants
High

Augmentation of current antidepressant (SSRI/SNRI) with mirtazapine (30 mg/d) vs augmentation of current antidepressant (various) with placebo

Quality of life (EQ‐5D‐5L) ‐ 12 weeks · treatment‐resistant depression in adults

1 finding from 1 review

Pharmacological interventions for treatment‐resistant depression in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 447 participants
High