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What do systematic reviews say?

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Evidence found and GRADE certainty

8 questions · 8 findings · 1 reviews · Skin

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No studies found 1 · 12.5%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 5 · 62.5%High 2 · 25%

Metronidazole vs placebo

HRQOL ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Metronidazole vs placebo

Participant‐assessed improvement in rosacea severity · Participants with rosacea
1 finding from 1 review

Metronidazole vs placebo

Proportion of participants with adverse event · Participants with rosacea

Metronidazole showed no clear difference in proportion of participants with adverse event compared with placebo (high certainty).

1 finding from 1 review

Metronidazole vs placebo

Physician‐assessed improvement in rosacea severity · Participants with rosacea

Metronidazole probably leads to higher physician‐assessed improvement in rosacea severity compared with placebo (moderate certainty).

1 finding from 1 review

Metronidazole vs placebo

Duration of remission · Participants with rosacea

Metronidazole probably leads to lower duration of remission compared with placebo (moderate certainty).

1 finding from 1 review