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Evidence found and GRADE certainty

16 questions · 16 findings · 1 reviews · Pregnancy and Childbirth

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No studies found 2 · 12.5%GRADE not reported 0 · 0%Very low 2 · 12.5%Low 7 · 43.8%Moderate 5 · 31.3%High 0 · 0%

Metoclopramide vs ondansetron

Intervention side effects: unable to sleep · Pregnant women with hyperemesis gravidarum

Metoclopramide showed no clear difference in intervention side effects: unable to sleep compared with ondansetron (low certainty).

1 finding from 1 review

Metoclopramide vs ondansetron

Adverse effects: dry mouth · Pregnant women with hyperemesis gravidarum

Metoclopramide probably leads to higher intervention side effects: dry mouth compared with ondansetron (moderate certainty).

1 finding from 1 review

Metoclopramide vs ondansetron

Frequency of adverse effects ‐ dizziness ( · Pregnant women with hyperemesis gravidarum

Metoclopramide showed no clear difference in intervention side effects: felt dizzy compared with ondansetron (low certainty).

1 finding from 1 review

Metoclopramide vs ondansetron

Severity, reduction or cessation in nausea/vomiting 2.Days of hospital admission 3. Pregnancy complications 4. Adverse fetal/neonatal outcomes · Pregnant women with hyperemesis gravidarum

The review found no eligible studies for this question.

1 finding from 1 review

Metoclopramide vs promethazine

Intervention side effects: unable to sleep · Pregnant women with hyperemesis gravidarum

Metoclopramide showed no clear difference in intervention side effects: unable to sleep compared with promethazine (low certainty).

1 finding from 1 review

Metoclopramide vs promethazine

Frequency of adverse effects ‐ dizziness ( · Pregnant women with hyperemesis gravidarum

Metoclopramide probably leads to lower intervention side effects: felt dizzy compared with promethazine (moderate certainty).

1 finding from 1 review

Metoclopramide vs promethazine

Gastrointestinal side effects (diarrhoea) ‐ not reported · Pregnant women with hyperemesis gravidarum

Metoclopramide showed no clear difference in intervention side effects: diarrhea compared with promethazine (low certainty).

1 finding from 1 review

Metoclopramide vs promethazine

Severity, reduction or cessation in nausea/vomiting 2. Number of episodes of emesis 3. Days of hospital admission 4. Pregnancy complications 5. Adverse fetal/neonatal outcomes · Pregnant women with hyperemesis gravidarum

The review found no eligible studies for this question.

1 finding from 1 review