Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Methotrexate vs 6‐MP or azathioprine

Failure to enter remission or possible remission at 16 weeks (Arora 1999) · adult patients with refractory Crohn's disease

It is very uncertain whether methotrexate changes failure to enter remission or possible remission at 24‐36 weeks… compared with 6‐MP or azathioprine (very low certainty).

1 finding from 1 review

Methotrexate for induction of remission in refractory Crohn's disease 2014 · Cochrane Headline outcomes only
RR 3.2 [0.37, 27.49]
1 study · 31 participants
Very low