Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Metformin vs clomiphene

Live birth rate per woman aParticipants with BMI ≥ 30 kg/m2 · women with polycystic ovary syndrome

It is very uncertain whether metformin changes live birth rate per woman aParticipants with BMI ≥ 30 kg/m2 compared with clomiphene citrate (very low certainty).

1 finding from 1 review · compare the 2 reviews

Metformin for ovulation induction (excluding gonadotrophins) in women with polycystic ovary syndrome 2019 · Cochrane Headline outcomes only
OR 0.3 [0.17, 0.52]
2 studies · 500 participants
Very low

Metformin vs clomiphene

Live birth rate per woman aParticipants with BMI < 30 kg/m2 or ≤ 32 kg/m2 · women with polycystic ovary syndrome

It is very uncertain whether metformin changes live birth rate per woman aParticipants with BMI < 30 kg/m2 or ≤ 32… compared with clomiphene citrate (very low certainty).

1 finding from 1 review · compare the 2 reviews

Metformin for ovulation induction (excluding gonadotrophins) in women with polycystic ovary syndrome 2019 · Cochrane Headline outcomes only
OR 1.71 [1, 2.94]
3 studies · 241 participants
Very low