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Evidence found and GRADE certainty

5 questions · 5 findings · 1 reviews · Oral Health

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Mesoporous silica (SiO2) vs Fluoride agent (e.g., NaF/SDF/KF/CaF2)

Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)

In the Self-Etch adhesive + chemical ACAD protocol network, Silica vs Fluorine showed no significant difference in 24 h bond strength (MD 1.441, 95% CI -5.099 to 7.980; Moderate certainty).

1 finding from 1 review

Mesoporous silica (SiO2) vs Calcium-based agent

Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)

In the Self-Etch adhesive + chemical ACAD protocol network, Silica vs Calcium showed no significant difference in 24 h bond strength (MD 1.964, 95% CI -5.802 to 9.730; Moderate certainty).

1 finding from 1 review

Mesoporous silica (SiO2) vs No biomimetic remineralization (control)

Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)

In the Self-Etch adhesive + chemical ACAD protocol network, Silica vs Control showed no significant difference in 24 h bond strength (MD 0.840, 95% CI -5.270 to 6.950; Low certainty).

1 finding from 1 review

Mesoporous silica (SiO2) vs Calcium phosphate agent (e.g., CPP-ACP, Ca/P-PILP, niobophosphate)

Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)

In the Self-Etch adhesive + chemical ACAD protocol network, Silica vs Calcium Phosphate showed no significant difference in 24 h bond strength (MD -0.699, 95% CI -7.633 to 6.234; Moderate certainty).

1 finding from 1 review

Mesoporous silica (SiO2) vs HEMA/EGDMA-based desensitizer

Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)

In the Self-Etch adhesive + chemical ACAD protocol network, Silica vs HEMA showed no significant difference in 24 h bond strength (MD -1.059, 95% CI -9.024 to 6.906; Moderate certainty).

1 finding from 1 review