Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 14.3%Low 6 · 85.7%Moderate 0 · 0%High 0 · 0%

Core symptoms of autism · Children aged 6 to 18 years with ASD

1 finding from 1 review

Memantine for autism spectrum disorder 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 181 participants
Very low

Adverse effects sufficient to stop treatment · Children aged 6 to 18 years with ASD

Memantine showed no clear difference in adverse effects Assessed by the study authors as those that were… compared with placebo (low certainty).

1 finding from 1 review

Memantine for autism spectrum disorder 2022 · Cochrane Headline outcomes only
OR 0.64 [0.17, 2.39]
2 studies · 144 participants
Low

Language · Children aged 6 to 18 years with ASD

1 finding from 1 review

Memantine for autism spectrum disorder 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 144 participants
Low

Memory (specific cognitive function) · Children aged 6 to 18 years with ASD

1 finding from 1 review

Memantine for autism spectrum disorder 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 23 participants
Low

Adaptive behaviour · Children aged 6 to 18 years with ASD

1 finding from 1 review

Memantine for autism spectrum disorder 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 23 participants
Low

Hyperactivity · Children aged 6 to 18 years with ASD

1 finding from 1 review

Memantine for autism spectrum disorder 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 121 participants
Low

Irritability · Children aged 6 to 18 years with ASD

1 finding from 1 review

Memantine for autism spectrum disorder 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 121 participants
Low