Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Infectious Diseases

No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Discontinuation of treatment due to side effects ( · Non‐immune adults and children travelling to malaria‐endemic settings

Mefloquine showed no clear difference in discontinuations due to adverse effects compared with doxycycline; GRADE not reported.

1 finding from 1 review

Mefloquine for preventing malaria during travel to endemic areas 2017 · Cochrane Headline outcomes only
RR 1.08 [0.41, 2.87]
4 studies · 763 participants
GRADE not reported

Discontinuation of medication due to adverse events · non‐immune adults and children travelling to or living in malaria‐endemic settings

Mefloquine led to higher discontinuation of drug due to adverse effects compared with atovaquone‐proguanil; GRADE not reported.

1 finding from 1 review

Mefloquine for preventing malaria during travel to endemic areas 2017 · Cochrane Headline outcomes only
RR 2.86 [1.53, 5.31]
3 studies · 1438 participants
GRADE not reported