Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

52 questions · 52 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 36 · 69.2%Very low 1 · 1.9%Low 1 · 1.9%Moderate 7 · 13.5%High 7 · 13.5%

Mefloquine vs doxycycline

Discontinuation of treatment due to side effects ( · Non‐immune adults and children travelling to malaria‐endemic settings

Mefloquine showed no clear difference in discontinuations due to adverse effects compared with doxycycline; GRADE not reported.

1 finding from 1 review

Mefloquine vs doxycycline

Abnormal thoughts or perceptions · Non‐immune adults and children travelling to malaria‐endemic settings

Mefloquine showed no clear difference in abnormal thoughts or perceptions compared with doxycycline; GRADE not reported.

1 finding from 1 review

Mefloquine vs atovaquone‐proguanil

Discontinuation of medication due to adverse events · non‐immune adults and children travelling to or living in malaria‐endemic settings

Mefloquine led to higher discontinuation of drug due to adverse effects compared with atovaquone‐proguanil; GRADE not reported.

1 finding from 1 review