Findings

What do systematic reviews say?

4 questions · 4 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 2 · 50%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 2 · 50%

Clinical malaria · non‐immune adults and children travelling to or living in malaria‐endemic settings

1 finding from 1 review

Mefloquine for preventing malaria during travel to endemic areas 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1293 participants
GRADE not reported

Clinical malaria · Non‐immune adults and children travelling to malaria‐endemic settings

Mefloquine showed no clear difference in clinical malaria compared with doxycycline; GRADE not reported.

1 finding from 1 review

Mefloquine for preventing malaria during travel to endemic areas 2017 · Cochrane Headline outcomes only
RR 1.35 [0.35, 5.19]
4 studies · 744 participants
GRADE not reported

Clinical malaria episodes during pregnancy · HIV‐uninfected pregnant women

Mefloquine showed no clear difference in clinical malaria episodes during pregnancy compared with sulfadoxine‐pyrimethamine (high certainty).

1 finding from 1 review

Mefloquine for preventing malaria in pregnant women 2018 · Cochrane Headline outcomes only
IRR 0.83 [0.65, 1.05]
2 studies · 2 participants
High

Clinical malaria episodes during pregnancy · HIV‐infected pregnant women

Mefloquine plus cotrimoxazole showed no clear difference in clinical malaria episodes during pregnancy compared with cotrimoxazole (high certainty).

1 finding from 1 review

Mefloquine for preventing malaria in pregnant women 2018 · Cochrane Headline outcomes only
IRR 0.76 [0.33, 1.76]
1 study · 1 participants
High