Findings

What do systematic reviews say?

6 questions · 7 findings · 1 reviews · Gynaecology and Fertility

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 14.3%Moderate 4 · 57.1%High 2 · 28.6%

Medical treatment vs placebo

Improvement in pain score (up to nine months after treatment): progesterone versus placebo · women with chronic pelvic pain

Medical treatment probably leads to higher improvement in pain score at end of treatment: progesterone versus… compared with placebo (moderate certainty).

2 findings from 1 review

Non‐surgical interventions for the management of chronic pelvic pain 2014 · Cochrane Headline outcomes only
Peto OR 3 [1.7, 5.31]
204 participants
Moderate
Non‐surgical interventions for the management of chronic pelvic pain 2014 · Cochrane Headline outcomes only
Peto OR 2.09 [1.18, 3.71]
204 participants
Moderate

Medical treatment vs placebo

Weight gain · women with chronic pelvic pain

Medical treatment leads to higher weight gain: progesterone versus placebo compared with placebo (high certainty).

1 finding from 1 review

Non‐surgical interventions for the management of chronic pelvic pain 2014 · Cochrane Headline outcomes only
Peto OR 7.82 [3.28, 18.65]
85 participants
High

Medical treatment vs placebo

Bloatedness: progesterone versus placebo · women with chronic pelvic pain

Medical treatment leads to higher bloatedness: progesterone versus placebo compared with placebo (high certainty).

1 finding from 1 review

Non‐surgical interventions for the management of chronic pelvic pain 2014 · Cochrane Headline outcomes only
Peto OR 3.2 [1.37, 7.47]
85 participants
High

Medical treatment vs placebo

Improvement in pain score: lofexidine versus placebo · women with chronic pelvic pain

Medical treatment showed no clear difference in improvement in pain score: lofexidine versus placebo compared with placebo (low certainty).

1 finding from 1 review

Non‐surgical interventions for the management of chronic pelvic pain 2014 · Cochrane Headline outcomes only
Peto OR 0.42 [0.11, 1.61]
39 participants
Low

Medical treatment vs placebo

Drowsiness/lethargy: lofexidine versus placebo · women with chronic pelvic pain

Medical treatment probably leads to higher drowsiness/lethargy: lofexidine versus placebo compared with placebo (moderate certainty).

1 finding from 1 review

Non‐surgical interventions for the management of chronic pelvic pain 2014 · Cochrane Headline outcomes only
Peto OR 3.8 [1.09, 13.26]
39 participants
Moderate

Medical treatment vs placebo

Dry mouth (xerostomia) · women with chronic pelvic pain

Medical treatment probably leads to higher dry mouth: lofexidine versus placebo compared with placebo (moderate certainty).

1 finding from 1 review

Non‐surgical interventions for the management of chronic pelvic pain 2014 · Cochrane Headline outcomes only
Peto OR 8.6 [2.44, 30.31]
39 participants
Moderate