What do systematic reviews say?

Mask vs prongs

Mask showed no clear difference in all‐cause mortality compared with prongs (low certainty).

• Masks versus prongs as interfaces for nasal continuous positive airway pressure in preterm infants 2022 · Cochrane Headline outcomes only
  RR 0.83 [0.56, 1.22]
  7 studies · 814 participants
  Low