What do systematic reviews say?

Lutein with or without zeaxanthin vs placebo

It is very uncertain whether lutein with or without zeaxanthin changes adverse effects compared with placebo (very low certainty).

• Antioxidant vitamin and mineral supplements for slowing the progression of age‐related macular degeneration 2023 · Cochrane Headline outcomes only
  OR 1.06
  Studies not reported
  Very low