Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

15 questions · 19 findings · 3 reviews · Oral Health

No studies found 4 · 21.1%GRADE not reported 9 · 47.4%Very low 5 · 26.3%Low 1 · 5.3%Moderate 0 · 0%High 0 · 0%

Low‐level laser therapy vs Conventional orthodontic appliance treatment

Discomfort/pain · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

It is very uncertain whether low level laser therapy (LLLT) changes patient perception of pain and discomfort (VAS 0 to 100 mm) compared with conventional orthodontic appliance treatment (very low certainty).

1 finding from 1 review

Low‐level laser therapy vs Conventional orthodontic appliance treatment

Patient-reported need for analgesics · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

The review found no eligible studies for this question.

1 finding from 1 review

Low‐level laser therapy vs Conventional orthodontic appliance treatment

Rate of maxillary molar intrusion for correction of anterior open bite · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment
1 finding from 1 review

Low‐level laser therapy vs Conventional orthodontic appliance treatment

Rate of orthodontic tooth movement during space closure stage (maxillary arch), mm/month · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

It is very uncertain whether low level laser therapy (LLLT) changes rate of orthodontic tooth movement during space closure stage… compared with conventional orthodontic appliance treatment (very low certainty).

1 finding from 1 review

Low‐level laser therapy vs Conventional orthodontic appliance treatment

Side effects or other adverse events · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment
1 finding from 1 review

Low‐level laser therapy vs Conventional orthodontic appliance treatment

Periodontal health during molar intrusion · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment
1 finding from 1 review

Low‐level laser therapy vs Conventional orthodontic appliance treatment

Total number of orthodontic appliance adjustment appointments during alignment stage · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

It is very uncertain whether low level laser therapy (LLLT) changes total number of orthodontic appliance adjustment appointments during… compared with conventional orthodontic appliance treatment (very low certainty).

1 finding from 1 review

Low‐level laser therapy vs Conventional orthodontic appliance treatment

Duration of orthodontic treatment during alignment stage · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

It is very uncertain whether low level laser therapy (LLLT) changes duration of orthodontic treatment during alignment stage compared with conventional orthodontic appliance treatment (very low certainty).

1 finding from 1 review

Low‐level laser therapy vs Conventional orthodontic appliance treatment

Total number of orthodontic appliance adjustment appointments during treatment · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

The review found no eligible studies for this question.

1 finding from 1 review

Low‐level laser therapy vs Conventional orthodontic appliance treatment

Overall treatment time wearing orthodontic appliances · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

The review found no eligible studies for this question.

1 finding from 1 review

Low‐level laser therapy vs Conventional orthodontic appliance treatment

Orthodontic tooth movement (OTM) during alignment stage · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

It is very uncertain whether low level laser therapy (LLLT) changes rate of orthodontic tooth movement during alignment stage… compared with conventional orthodontic appliance treatment (very low certainty).

1 finding from 1 review

Low‐level laser therapy vs Conventional orthodontic appliance treatment

Orthodontically-induced inflammatory root resorption (OIIRR) during molar intrusion · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment
1 finding from 1 review

Low‐level laser therapy vs Placebo (or no irradiation)

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents and adults undergoing orthodontic treatment

Low‐level laser therapy (LLLT) showed no clear difference in patient‐reported pain intensity or pain relief (VAS, NRS or… compared with placebo (or no irradiation); GRADE not reported.

5 findings from 1 review
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Low‐level laser therapy vs Placebo (sham) laser therapy

Mucositis severity (mild to moderate) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis

Low level laser therapy led to higher mucositis severity (mild to moderate) compared with sham (placebo) laser treatment; GRADE not reported.

1 finding from 1 review