Low‐dose colchicine vs placebo
Pain ‐ not reported · acute gout
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Findings
What do systematic reviews say?
14 questions · 14 findings · 1 reviews · Musculoskeletal
No studies found 7 · 50%GRADE not reported 2 · 14.3%Very low 0 · 0%Low 5 · 35.7%Moderate 0 · 0%High 0 · 0%
Low‐dose colchicine vs placebo
Participant global assessment of treatment success: proportion with 50% or greater decrease in pain score from baseline ‐ 32 to 36 hours · acute gout
Low‐dose colchicine may leads to higher participant global assessment of treatment success: proportion with… compared with placebo (low certainty).
1 finding from 1 review
- RR 2.43 [1.05, 5.64]1 study · 103 participantsLow
Low‐dose colchicine vs NSAIDs
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · acute gout
1 finding from 1 review
- no estimate extracted1 study · 399 participantsLow
Low‐dose colchicine vs NSAIDs
Global assessment of treatment success · acute gout
Low‐dose colchicine showed no clear difference in participant global assessment of treatment success: Completely… compared with NSAIDs (low certainty).
1 finding from 1 review
- RR 0.97 [0.82, 1.15]1 study · 399 participantsLow
Low‐dose colchicine vs NSAIDs
Reduction of inflammation ‐ not measured · acute gout
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Low‐dose colchicine vs NSAIDs
Function of target joint ‐ not measured · acute gout
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Low‐dose colchicine vs NSAIDs
Serious adverse events · acute gout
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Low‐dose colchicine vs NSAIDs
Number of participants reporting an adverse event · acute gout
Low‐dose colchicine showed no clear difference in total number of participants reporting adverse events compared with NSAIDs (low certainty).
1 finding from 1 review
- RR 1.07 [0.88, 1.29]1 study · 399 participantsLow
Low‐dose colchicine vs NSAIDs
Withdrawals due to adverse events · acute gout
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Low‐dose colchicine vs placebo
Reduction of inflammation ‐ not measured · acute gout
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Low‐dose colchicine vs placebo
Function of target joint ‐ not measured · acute gout
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Low‐dose colchicine vs placebo
Serious adverse events · acute gout
1 finding from 1 review
- no estimate extracted1 study · 133 participantsGRADE not reported
Low‐dose colchicine vs placebo
Total adverse events · acute gout
Low‐dose colchicine showed no clear difference in total adverse events compared with placebo (low certainty).
1 finding from 1 review
- RR 1.32 [0.68, 2.56]1 study · 103 participantsLow
Low‐dose colchicine vs placebo
Withdrawals due to adverse events · acute gout
1 finding from 1 review
- no estimate extracted1 study · 133 participantsGRADE not reported