Findings

What do systematic reviews say?

27 questions · 27 findings · 2 reviews

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No studies found 4 · 14.8%GRADE not reported 1 · 3.7%Very low 2 · 7.4%Low 17 · 63%Moderate 3 · 11.1%High 0 · 0%

Loratadine 10 mg vs placebo (2‐week intervention)

Secondary outcome: quality of life · adults with eczema

The review found no eligible studies for this question.

1 finding from 1 review

Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Loratadine 10 mg vs placebo (2‐week intervention)

Secondary outcome: clinical flare · adults with eczema

The review found no eligible studies for this question.

1 finding from 1 review

Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Desloratadine 5 to 20 mg vs placebo

Complete suppression of urticaria: short‐term duration of intervention (desloratadine 5 mg) Global assessment of symptom scores · patients with chronic spontaneous urticaria

1 finding from 1 review

H1‐antihistamines for chronic spontaneous urticaria 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 46 participants
Low

Desloratadine 5 to 20 mg vs placebo

Complete suppression of urticaria: short‐term duration of intervention (desloratadine 10 mg) Global assessment of symptom scores · patients with chronic spontaneous urticaria

1 finding from 1 review

H1‐antihistamines for chronic spontaneous urticaria 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 46 participants
Low

Desloratadine 5 to 20 mg vs placebo

Complete suppression of urticaria: short‐term duration of intervention (desloratadine 20 mg) Global assessment of symptom scores · patients with chronic spontaneous urticaria

1 finding from 1 review

H1‐antihistamines for chronic spontaneous urticaria 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 46 participants
Low

Desloratadine 5 to 20 mg vs placebo

Complete suppression of urticaria: intermediate‐term duration of intervention (desloratadine 5 mg) Global assessment of symptom scores · patients with chronic spontaneous urticaria

1 finding from 1 review

H1‐antihistamines for chronic spontaneous urticaria 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 80 participants
Low

Desloratadine 5 to 20 mg vs placebo

Adverse effects requiring withdrawal/discontinuation of study medication · patients with chronic spontaneous urticaria

Desloratadine 5 to 20 mg showed no clear difference in adverse effects leading to withdrawal: intermediate‐term duration of… compared with placebo (low certainty).

1 finding from 1 review

H1‐antihistamines for chronic spontaneous urticaria 2014 · Cochrane Headline outcomes only
RR 1.46 [0.42, 5.1]
3 studies · 466 participants
Low