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What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 2 findings · 1 reviews · Common Mental Disorders

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%

Lithium vs carbamazepine

Adverse effects: 1. Sedation · acute mania

Lithium showed no clear difference in adverse event: sedation compared with carbamazepine (low certainty).

1 finding from 1 review

Lithium vs ARIPIPRAZOLE

Adverse events: somnolence/sedation · acute mania

Lithium showed no clear difference in adverse events: somnolence/sedation compared with aripiprazole (moderate certainty).

1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    OR 0.56 [0.26, 1.23]
    1 study · 313 participants
    Moderate