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Evidence found and GRADE certainty

5 questions · 5 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 40%Low 2 · 40%Moderate 0 · 0%High 1 · 20%

Lithium vs placebo

Efficacy: response (continuous) Change in YMRS (ITT‐LOCF) from baseline to end of study · acute mania
1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    no estimate extracted
    4 studies · 935 participants
    High

Lithium vs QUETIAPINE

Efficacy: response (continuous) Change in YMRS (ITT‐LOCF) from baseline to end of study · acute mania
1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    no estimate extracted
    2 studies · 359 participants
    Low

Lithium vs carbamazepine

Efficacy: response (continuous) YMRS/BPRS change from baseline to end of study · acute mania
1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    no estimate extracted
    3 studies · 102 participants
    Very low

Lithium vs valproate

Efficacy: response (continuous) Change in YMRS (ITT‐LOCF) from baseline to end of study · acute mania
1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    no estimate extracted
    5 studies · 398 participants
    Very low