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Evidence found and GRADE certainty

1 questions · 1 findings · 1 reviews

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Lithium vs placebo

Efficacy: response (categorical) MSRS/YMRS ≥ 50% decrease in score by end of study · acute mania

Lithium leads to higher efficacy: response (categorical) YMRS/MRS decrease by ≥ 50% at end… compared with placebo (high certainty).

1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    OR 2.13 [1.73, 2.63]
    6 studies · 1707 participants
    High