Findings

What do systematic reviews say?

8 questions · 8 findings · 1 reviews · Stroke

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No studies found 5 · 62.5%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 37.5%Moderate 0 · 0%High 0 · 0%

Lipid‐lowering agent vs placebo or no treatment

Ipsilateral major or disabling stroke · asymptomatic carotid stenosis

Lipid‐lowering agent showed no clear difference in ipsilateral major or disabling stroke (only reported for two… compared with placebo or no treatment (low certainty).

1 finding from 1 review

Pharmacological interventions for asymptomatic carotid stenosis 2023 · Cochrane Headline outcomes only
RR 0.36 [0.09, 1.53]
5 studies · 2235 participants
Low

Lipid‐lowering agent vs placebo or no treatment

Stroke‐related mortality · asymptomatic carotid stenosis

Lipid‐lowering agent showed no clear difference in stroke‐related mortality (only reported for one study: CT scan, MRI… compared with placebo or no treatment (low certainty).

1 finding from 1 review

Pharmacological interventions for asymptomatic carotid stenosis 2023 · Cochrane Headline outcomes only
RR 0.25 [0.03, 2.29]
2 studies · 1366 participants
Low

Lipid‐lowering agent vs placebo or no treatment

Adverse events (hospital records/every 6 weeks) · asymptomatic carotid stenosis

Lipid‐lowering agent showed no clear difference in adverse events (only reported for two studies: one study used CT… compared with placebo or no treatment (low certainty).

1 finding from 1 review

Pharmacological interventions for asymptomatic carotid stenosis 2023 · Cochrane Headline outcomes only
RR 0.76 [0.53, 1.1]
7 studies · 3726 participants
Low