Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

35 questions · 35 findings · 5 reviews

No studies found 10 · 28.6%GRADE not reported 3 · 8.6%Very low 4 · 11.4%Low 16 · 45.7%Moderate 1 · 2.9%High 1 · 2.9%

Lifestyle interventions vs placebo or usual care

Overall survival (24 months) · weight reduction in obesity to improve survival in women with endometrial cancer

It is very uncertain whether summary of findings table ‐ Lifestyle intervention changes overall survival (24 months) compared with usual care compared to placebo (very low certainty).

1 finding from 1 review

Lifestyle interventions vs placebo or usual care

Adverse events – musculoskeletal · weight reduction in obesity to improve survival in women with endometrial cancer

It is very uncertain whether summary of findings table ‐ Lifestyle intervention changes adverse events – musculoskeletal compared with usual care compared to placebo (very low certainty).

1 finding from 1 review

Lifestyle interventions vs placebo or usual care

Cardiovascular and metabolic event frequency (12 months) (Number of strokes, myocardial infarctions and hospitalisations for heart failure) · weight reduction in obesity to improve survival in women with endometrial cancer

Summary of findings table ‐ Lifestyle intervention showed no clear difference in cardiovascular and metabolic event frequency (6 months) compared with usual care compared to placebo (low certainty).

1 finding from 1 review