Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4 questions · 4 findings · 1 reviews · Neonatal

No studies found 1 · 25%GRADE not reported 0 · 0%Very low 1 · 25%Low 2 · 50%Moderate 0 · 0%High 0 · 0%

Anti‐vascular endothelial growth factor therapy combined with laser/cryotherapy vs conventional laser/cryotherapy

Structural outcome ‐ retinal detachment · preterm infants with type 1 ROP

Anti‐vascular endothelial growth factor therapy combined with… may leads to lower structural outcome ‐ retinal detachment (unit of analysis: eyes) compared with laser/cryotherapy (low certainty).

1 finding from 1 review

Anti‐vascular endothelial growth factor therapy combined with laser/cryotherapy vs conventional laser/cryotherapy

Local adverse effects ‐ perioperative retinal haemorrhages (unit of analysis: eyes) · preterm infants with type 1 ROP

It is very uncertain whether anti‐vascular endothelial growth factor therapy combined with… changes local adverse effects ‐ perioperative retinal haemorrhages (unit of… compared with laser/cryotherapy (very low certainty).

1 finding from 1 review

Anti‐vascular endothelial growth factor therapy combined with laser/cryotherapy vs conventional laser/cryotherapy

Recurrence of ROP by 55 weeks' PMA · preterm infants with type 1 ROP

Anti‐vascular endothelial growth factor therapy combined with… may leads to lower recurrence of ROP by 55 weeks' postmenstrual age compared with laser/cryotherapy (low certainty).

1 finding from 1 review