What do systematic reviews say?

Laparoscopic vs open surgery

Laparoscopic surgery showed no clear difference in septic abdominal complications (presence or absence) Clinical… compared with open surgery (low certainty).

• Laparoscopic repair for perforated peptic ulcer disease 2013 · Cochrane Headline outcomes only
  OR 0.66 [0.3, 1.47]
  2 studies · 214 participants
  Low

Laparoscopic vs open surgery

Laparoscopic surgery showed no clear difference in pulmonary complications (presence or absence) compared with open surgery (low certainty).

• Laparoscopic repair for perforated peptic ulcer disease 2013 · Cochrane Headline outcomes only
  OR 0.52 [0.08, 3.55]
  3 studies · 315 participants
  Low

Laparoscopic vs open surgery

Laparoscopic surgery showed no clear difference in surgical site infection compared with open surgery (moderate certainty).

• Laparoscopic repair for perforated peptic ulcer disease 2013 · Cochrane Headline outcomes only
  OR 0.28 [0.08, 1]
  3 studies · 315 participants
  Moderate

Laparoscopic vs open surgery

Laparoscopic surgery showed no clear difference in suture dehiscence compared with open surgery (low certainty).

• Laparoscopic repair for perforated peptic ulcer disease 2013 · Cochrane Headline outcomes only
  OR 1.52 [0.29, 7.98]
  3 studies · 315 participants
  Low

Laparoscopic vs open surgery

Laparoscopic surgery showed no clear difference in postoperative ileus compared with open surgery (low certainty).

• Laparoscopic repair for perforated peptic ulcer disease 2013 · Cochrane Headline outcomes only
  OR 0.54 [0.16, 1.8]
  3 studies · 315 participants
  Low

Laparoscopic vs open surgery

It is very uncertain whether laparoscopic surgery changes intra‐abdominal abscess compared with open surgery (very low certainty).

• Laparoscopic repair for perforated peptic ulcer disease 2013 · Cochrane Headline outcomes only
  OR 1.15 [0.33, 4.03]
  3 studies · 315 participants
  Very low

Laparoscopic vs open surgery

• Laparoscopic repair for perforated peptic ulcer disease 2013 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 214 participants
  Very low

Laparoscopic vs diagnostic laparoscopy

Laparoscopic surgery may leads to higher ongoing pregnancy at 20 weeks or live birth compared with diagnostic laparoscopy (low certainty).

• Laparoscopic surgery for subfertility associated with endometriosis 2010 · Cochrane Headline outcomes only
  OR 1.64 [1.05, 2.57]
  2 studies · 437 participants
  Low

Laparoscopic vs diagnostic laparoscopy

It is very uncertain whether laparoscopic surgery changes pregnancy compared with diagnostic laparoscopy (very low certainty).

• Laparoscopic surgery for subfertility associated with endometriosis 2010 · Cochrane Headline outcomes only
  OR 1.66 [1.09, 2.51]
  2 studies · 437 participants
  Very low

Laparoscopic vs diagnostic laparoscopy

Laparoscopic surgery showed no clear difference in fetal loss per couple randomised compared with diagnostic laparoscopy (low certainty).

• Laparoscopic surgery for subfertility associated with endometriosis 2010 · Cochrane Headline outcomes only
  OR 1.33 [0.6, 2.94]
  2 studies · 437 participants
  Low

Laparoscopic vs diagnostic laparoscopy

Laparoscopic surgery showed no clear difference in operative complications compared with diagnostic laparoscopy (low certainty).

• Laparoscopic surgery for subfertility associated with endometriosis 2010 · Cochrane Headline outcomes only
  OR 2.69 [0.38, 19.3]
  1 study · 341 participants
  Low