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Evidence found and GRADE certainty

6 questions · 6 findings · 1 reviews · Common Mental Disorders

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No studies found 0 · 0%GRADE not reported 1 · 16.7%Very low 1 · 16.7%Low 0 · 0%Moderate 4 · 66.7%High 0 · 0%

Lamotrigine vs lithium

Withdrawal from treatment due to any reason, 6‐12 months after intervention initiation (long term) · bipolar disorder

Lamotrigine showed no clear difference in withdrawal from treatment due to any reason, 6‐12 months after… compared with lithium (moderate certainty).

1 finding from 1 review

Lamotrigine vs lithium

Any reported adverse effects 6‐12 months after initiating the intervention (long term) · bipolar disorder

Lamotrigine probably leads to lower any reported adverse effects 6‐12 months after initiating the… compared with lithium (moderate certainty).

1 finding from 1 review

Lamotrigine vs placebo

Withdrawal from treatment due to any reason, 6‐12 months after intervention initiation (long term) · bipolar disorder

Lamotrigine probably leads to lower withdrawal from treatment due to any reason, 6‐12 months after… compared with placebo (moderate certainty).

1 finding from 1 review

Lamotrigine vs placebo

Any reported adverse effects 6‐12 months after initiating the intervention (long term) · bipolar disorder

Lamotrigine showed no clear difference in any reported adverse effects 6‐12 months after initiating the… compared with placebo (moderate certainty).

1 finding from 1 review