Postbiotics from Lactobacillus spp. (cell-free supernatants, biosurfactants, lipoteichoic acid, bacterial lysates) vs No prior SDF application (untreated dentin control)
Reduced enamel demineralization · Cariogenic bacteria (mainly Streptococcus mutans reference strains) and oral biofilms in vitro
A single in vitro study found postbiotics reduce enamel demineralization (ungraded).
1 finding from 1 review
- Postbiotics and Dental Caries: A Systematic Review. 2025 All outcomesExposure 24 h to 7 days · Laboratory (in vitro)One in vitro multispecies-biofilm study reported that a postbiotic (L. reuteri cell-free supernatant) reduced enamel demineralization, indicating a protective effect against caries; no pooled estimate.1 studyGRADE not reported