Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Gynaecology and Fertility

No studies found 1 · 14.3%GRADE not reported 0 · 0%Very low 1 · 14.3%Low 1 · 14.3%Moderate 4 · 57.1%High 0 · 0%

Treatment withdrawal for any reason Duration of treatment (range): 12 (3 months) to 36 weeks · heavy menstrual bleeding

LNG‐IUS probably leads to lower withdrawal from treatment for any reason compared with any other medical treatment (moderate certainty).

1 finding from 1 review

Progestogen‐releasing intrauterine systems for heavy menstrual bleeding 2020 · Cochrane Headline outcomes only
RR 0.49 [0.39, 0.6]
1 study · 571 participants
Moderate

Treatment failure · heavy menstrual bleeding

LNG‐IUS probably leads to lower treatment failure compared with any other medical treatment (moderate certainty).

1 finding from 1 review

Progestogen‐releasing intrauterine systems for heavy menstrual bleeding 2020 · Cochrane Headline outcomes only
RR 0.34 [0.26, 0.44]
6 studies · 535 participants
Moderate

Bleeding · heavy menstrual bleeding

1 finding from 1 review

Progestogen‐releasing intrauterine systems for heavy menstrual bleeding 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 170 participants
Low

Satisfaction · heavy menstrual bleeding

It is very uncertain whether LNG‐IUS changes satisfaction compared with any other medical treatment (very low certainty).

1 finding from 1 review

Progestogen‐releasing intrauterine systems for heavy menstrual bleeding 2020 · Cochrane Headline outcomes only
RR 1.28 [1.01, 1.63]
3 studies · 141 participants
Very low

Quality of life · heavy menstrual bleeding

1 finding from 1 review

Progestogen‐releasing intrauterine systems for heavy menstrual bleeding 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 571 participants
Moderate

Adverse events · heavy menstrual bleeding

LNG‐IUS probably leads to lower adverse events compared with any other medical treatment (moderate certainty).

1 finding from 1 review

Progestogen‐releasing intrauterine systems for heavy menstrual bleeding 2020 · Cochrane Headline outcomes only
RR 0.91
1 study · 571 participants
Moderate

Costs · heavy menstrual bleeding

The review found no eligible studies for this question.

1 finding from 1 review

Progestogen‐releasing intrauterine systems for heavy menstrual bleeding 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found