Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

33 questions · 33 findings · 2 reviews

No studies found 4 · 12.1%GRADE not reported 0 · 0%Very low 16 · 48.5%Low 3 · 9.1%Moderate 10 · 30.3%High 0 · 0%

LMWH prophylaxis vs UFH

Adverse events (Re‐operation for bleeding (reoperation for major bleeding within 30 days (yes/no))) · People with cancer with perioperative thromboprophylaxis

LMWH prophylaxis showed no clear difference in reoperation for bleeding compared with UFH prophylaxis (moderate certainty).

1 finding from 1 review

LMWH prophylaxis vs UFH

Adverse effects sufficient to stop treatment · pregnant women at increased risk of VTE during pregnancy and the early postnatal period

It is very uncertain whether antenatal (± postnatal) prophylaxis: LMWH changes adverse effects sufficient to stop treatment compared with UFH (very low certainty).

1 finding from 1 review

LMWH prophylaxis vs UFH

Symptomatic thromboembolic events ( · pregnant women at increased risk of VTE during pregnancy and the early postnatal period

It is very uncertain whether antenatal (± postnatal) prophylaxis: LMWH changes symptomatic thromboembolic events ( compared with UFH (very low certainty).

1 finding from 1 review

Peripartum/postnatal prophylaxis (caesarean): LMWH vs UFH

Symptomatic thromboembolic events ( · women giving birth by elective or emergency caesarean (elective or emergency (1 trial), elective cesarean only (1 trial),…

It is very uncertain whether peripartum/postnatal prophylaxis (caesarean): LMWH changes symptomatic thromboembolic events (timing of assessment unclear,… compared with UFH (very low certainty).

1 finding from 1 review

Peripartum/postnatal prophylaxis (caesarean): LMWH vs UFH

Symptomatic DVT · women giving birth by elective or emergency caesarean (elective or emergency (1 trial), elective cesarean only (1 trial),…

It is very uncertain whether peripartum/postnatal prophylaxis (caesarean): LMWH changes symptomatic DVT (timing of assessment unclear, within 6 weeks… compared with UFH (very low certainty).

1 finding from 1 review

Peripartum/postnatal prophylaxis (caesarean): LMWH vs UFH

Adverse effects sufficient to stop treatment · women giving birth by elective or emergency caesarean (elective or emergency (1 trial), elective cesarean only (1 trial),…

The review found no eligible studies for this question.

1 finding from 1 review