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Evidence found and GRADE certainty

5 questions · 5 findings · 1 reviews

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No studies found 1 · 20%GRADE not reported 0 · 0%Very low 4 · 80%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

L‐ornithine L‐aspartate vs lactulose

Non‐serious adverse events assessed using ICH‐GCP · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

It is very uncertain whether L‐ornithine L‐aspartate changes non‐serious adverse events assessed using ICH‐GCP compared with lactulose (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs lactulose

All‐cause mortality · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

It is very uncertain whether L‐ornithine L‐aspartate changes mortality compared with lactulose (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs lactulose

Hepatic encephalopathy · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

It is very uncertain whether L‐ornithine L‐aspartate changes hepatic encephalopathy assessed based on neurocognitive manifestations compared with lactulose (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs lactulose

Serious adverse events assessed using ICH‐GCP · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

It is very uncertain whether L‐ornithine L‐aspartate changes serious adverse events assessed using ICH‐GCP compared with lactulose (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs lactulose

Quality of life assessed using questionnaires · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

The review found no eligible studies for this question.

1 finding from 1 review