What do systematic reviews say?

Ketoconazole vs placebo

Ketoconazole may leads to lower failure to achieve complete resolution Clinical assessment compared with placebo (low certainty).

• Topical antifungals for seborrhoeic dermatitis 2015 · Cochrane Headline outcomes only
  RR 0.69 [0.59, 0.81]
  8 studies · 2520 participants
  Low

Ketoconazole vs steroids

Ketoconazole showed no clear difference in failure to achieve complete resolution (combined for face and scalp)… compared with steroids (low certainty).

• Topical antifungals for seborrhoeic dermatitis 2015 · Cochrane Headline outcomes only
  RR 1.17 [0.95, 1.44]
  6 studies · 302 participants
  Low

Ketoconazole vs steroids

• Topical antifungals for seborrhoeic dermatitis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 80 participants
  Very low

Ketoconazole vs ciclopirox

Ketoconazole showed no clear difference in failure to achieve complete resolution ‐ Face only Clinical assessment compared with ciclopirox (low certainty).

• Topical antifungals for seborrhoeic dermatitis 2015 · Cochrane Headline outcomes only
  RR 1.09 [0.95, 1.26]
  3 studies · 447 participants
  Low

Ketoconazole vs ciclopirox

Ketoconazole showed no clear difference in failure to achieve complete resolution (long term) ‐ Face only… compared with ciclopirox (low certainty).

• Topical antifungals for seborrhoeic dermatitis 2015 · Cochrane Headline outcomes only
  RR 1.16 [0.98, 1.38]
  2 studies · 339 participants
  Low